No, that's not possible, legally nor technically. In order to know that you would need to ask permission to access the recipient's email inbox, which is not a realistic, practical nor ethical option.
If your email has not been opened after a long time then there's a possibility it has gone to spam. If you are worried that your emails are going to spam then there are deliverability best practices that you can follow in order to make sure that your emails are delivered to inbox, such as not putting lots of images in your email, avoiding using certain words in the subject line e.g. free, urgent, writing the subject line all in caps etc.
If your email has not been opened after a long time then there's a possibility it has gone to spam. If you are worried that your emails are going to spam then there are deliverability best practices that you can follow in order to make sure that your emails are delivered to inbox, such as not putting lots of images in your email, avoiding using certain words in the subject line e.g. free, urgent, writing the subject line all in caps etc.